Everything about Muscle Biopsy totally explained
In
medicine, a
muscle biopsy is a procedure in which a piece of
muscle tissue is removed from an
organism and examined
microscopically. A
biopsy needle is usually inserted into a muscle, wherein a small amount of tissue remains. Alternatively, an "open biopsy" can be performed by obtaining the muscle tissue through a small surgical incision. A muscle biopsy can lead to the discovery of problems with a
nervous system,
connective tissue,
vascular system, or
musculoskeletal system. In humans with weakness and low muscle tone, a muscle biopsy can help distinguish between
myopathies (where the pathology is in the muscle tissue itself) and
neuropathies (where the pathology is at the nerves innervating those muscles). Muscle biopsies can also help to distinguish among various types of
myopathies, by microscopic analysis for differing characteristics when exposed to a variety of chemical reactions and stains.
However, in some cases the muscle biopsy alone is inadequate to distinguish between certain myopathies. For example, a muscle biopsy showing the nucleus pathologically located in the center of the muscle cell would indicate "
centronuclear myopathy", but research has shown that a variety of
myopathies can cause these centronuclear biopsy appearance, and hence the specific
genetic testing becomes increasingly important.
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Additionally muscle biopsy is the only certain way to clarify ones muscle fiber types. I.e. by undergoing a muscle biopsy one can get a clear picture of which type of muscles dominates his/hers body.
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